Does angiotensin-converting enzyme polymorphism have association with symptomatic benign prostatic hyperplasia?

Association of angiotensin-converting enzyme insertion-deletion polymorphism with preeclampsia.

The aim of this study was to determine if insertion-deletion polymorphism of angiotensin-converting enzyme is a risk factor for the development of preeclampsia. Sixty women with preeclampsia and 50 normotensive pregnant women were included in this study. Preeclampsia was defined as blood pressure >140/90 mmHg in a previously normotensive women with proteinuria >300 mg/L in a 24-hours. Twelve wo...

Angiotensin Converting Enzyme in Sarcoidosis

Angiotensin-converting Enzyme Genetic Polymorphism

Indeed, the sample size limitation is a universal bias in all of the genetic polymorphisms in heart failure and the ACE-genotype was no different. The metanalysis by Bai et al.1. with 17 different studies included 2.453 cases (i.e. heart failure patients) from all over the world with only 60.3% being white individuals. The author concluded that there was no association between ACE DD genotype a...

Angiotensin Converting Enzyme Gene Polymorphism in Iranian Patients with Type 2 Diabetes

Background: Angiotensin I converting enzyme (ACE) is a Zinc metalloproteinase, converts Ang-I to Ang- II, a pro-inflammatory agent which may contribute to pathophysiology of some diseases like type 2 diabetes. Objective: To investigate the relationship between ACE I/D polymorphism and type 2 diabetes in 261 Iranian casecontrol pairs. Methods: 170 patients (85 type 2 diabetics with nephropathy a...

association of catechol-o-methyl transferase gene polymorphism with prostate cancer and benign prostatic hyperplasia

background : a single nucleotide variation within  atechol-o-methyl transferase (comt) gene may alter the comt enzyme activity level. polymorphism of val158met in the comt gene has been related to malignancy. in this regard, a study was carried out to find a possible association between the comt gene polymorphism in patients with sporadic prostate cancer (pca) and benign prostatic hyperplasia (...